已发表文献

Adhesion 

Dynamic monitoring of cell adhesion and spreading on microelectronic sensor arrays

Atienza JM, Zhu J, Wang X, Xu X, Abassi Y.

J Biomol Screen. 2005 Dec;10(8):795-805. Epub 2005 Oct 18.

Cytotoxicity and Proliferation

Potent siRNA Inhibitors of Ribonucleotide Reductase Subunit RRM2 Reduce Cell Proliferation In vitro and In vivo

Heidel JD, Liu JY, Yen Y, Zhou B, Heale BS, Rossi JJ, Bartlett DW, and Davis ME

Clin Cancer Res. 2007 April;13(7):2207-15.   

Dynamic detection of natural killer cell-mediated cytotoxicity and cell adhesion by electrical impedance measurements.

JGlamann J, Hansen AJ.

Assay Drug Dev Technol. 2006 Oct;4(5):555-63.

Synthesis and anti-tumor evaluation of new trisulfide derivatives.

An H, Zhu J, Wang X, Xu X.

Bioorg Med Chem Lett. 2006 Sep 15;16(18):4826-9. Epub 2006 Jul 7.

Microelectronic cell sensor assay for detection of cytotoxicity and prediction of acute toxicity

Xing JZ, Zhu L, Gabos S, Xie L.

Toxicol In Vitro. 2006 Sep;20(6):995-1004. Epub 2006 Feb 14.

Dynamic and label-free monitoring of natural killer cell cytotoxic activity using electronic cell sensor arrays.

Zhu J, Wang X, Xu X, Abassi YA.

J Immunol Methods. 2006 Feb 20;309(1-2):25-33. Epub 2006 Jan 4.

Down-regulation of Hepatoma-Derived Growth Factor Inhibits Anchorage-Independent Growth and Invasion of Non-Small Cell Lung Cancer Cells

Zhang J, Hening R, Yuan P, Lang W, Zhang L, Mao L.

Cancer Research. January 2006; 66(1):18-23.

Yeast beta-glucan amplifies phagocyte killing of iC3b-opsonized tumor cells via complement receptor 3-Syk-phosphatidylinositol 3-kinase pathway

Li B, Allendorf DJ, Hansen R, Marroquin J, Ding C, Cramer DE, Yan J.

The Journal of Immunology.2006 Aug 1;177(3):1661-9

Dynamic monitoring of cytotoxicity on microelectronic sensors

Xing JZ, Zhu L, Jackson JA, Gabos S, Sun XJ, Wang XB, Xu X.

Chem Res Toxicol. 2005 Feb;18(2):154-61.

The ribonucleotide reductase subunit M2B subcellular localization and functional importance for DNA replication in physiological growth of KB cells

Liu X, Zhou B, Xue L, Shih J, Tye K, Qi C, Yen Y.

Biochem Pharm. 2005; 70:1288-1297.

Application of real-time cell electronic sensing (RT-CES) technology to

cell-based assays

Solly K, Wang X, Xu X, Strulovici B, Zheng W.

Assay Drug Dev Technol. 2004 Aug;2(4):363-72.

Deletion of Shp2 in the Brain Leads to Defective Proliferation and Differentiation in Neural Stem Cells and Early Postnatal Lethality

Yuehai Ke, Eric E. Zhang, Kazuki Hagihara, Dongmei Wu, Yuhong Pang, Rudiger Klein, Tom Curran, Barbara Ranscht, and Gen-Sheng Feng*

Mol. Cell. Biol. doi:10.1128/MCB.01225-07

Effects of promyelocytic leukemia zinc finger protein on the proliferation of cultured human corneal edothelial cells

Takeshi Joko, Daisuke Nanba, Fumio Shiba, Kazunori Miyata, Atsushi Shiraishi, Yuichi Ohashi, Shigeki Higashiyama

Molecular Vision 2007; 13:649-58

Combined Yeast B-Glucan and Antitumor Monoclonal Antibody Therapy Requires C5a-Mediated Neutrophil Chemotaxis via Regulation of Decay-Accelerating Factor CD55

Bing Li, Daniel J. Allendorf, Richard Hansen, Jose Marroquin, Daniel E. Cramer, Claire L. Harris, and Jun Yan

Cancer Res 2007; 67:(15). August 1, 2007

Compound Cytotoxicity Profiling Using Quantitative High-Throughput ScreeningMenghang Xia, Ruili Huang, Kristine L. Witt, Noel Southall, Jennifer Fostel, Ming-Hsuang Cho, Ajit Jadhav, Cynthia S. Smith, James Inglese, Christopher J. Portier, Raymond R. Tice and Christopher P. Austin

Environmental Health Perspectives, doi:10.1289/ehp.10727, November 22, 2007   

Ectopic expression of methionine aminopeptidase-2 causes cell transformation and stimulates proliferation

LA Tucker, Q Zhang, GS Sheppard, P Lou, F Jian, E McKeegan, R Lesniewski, SK Davidsen, RL Bell and J Wang

Cancer Research, GPRD, Abbott Laboratories, Abbott Park, IL, USA. Oncogene (2008), 1-10

A cell-microelectronic sensing technique for profiling cytotoxicity of chemicals

Jessica M. Boyd, Li Huang, Li Xie, Birget Moe, Stephan Gabos, Xing-Fang Li

ScienceDirect ACA-229103;

Ectopic expression of methionine aminopeptidase-2 causes cell

transformation and stimulates proliferation

LA Tucker, Q Zhang, GS Sheppard, P Lou, F Jiang, E McKeegan, R Lesniewski, SK Davidsen, RL Bell and J Wang.

Oncogene (2008), 1–10

Migration

Role of Gab2 in mammary tumorigenesis and metastasis

Ke Y, Wu D, Princen F, Nguyen T, Pang Y, Lesperance J, Muller WJ, Oshima RG,Feng GS.

Oncogene. 2007 Feb 19; [Epub ahead of print]

An Orally Available Small-Molecule Inhibitor of c-Met, PF-2341066, Exhibits Cytoreductive Antitumor Efficacy through Antiproliferative and Antiangiogenic Mechanisms.

Helen Y. Zou, Qiuhua Li, Joseph H. Lee, Maria E. Arango, Scott R. McDonnell, Shinji Yamazaki, Tatiana B. Koudriakova, Gordon Alton, Jingrong J. Cui, Pei-Pei Kung, Mitchell D. Nambu, Cerrit Los, Steven L. Bender, Barbara Mroczkowski, and James G. Christensen.

Cancer Res 2007;67:(9). May 1, 2007.    

Quality Control

Live cell quality control and utility of real-time cell electronic sensing for assay development.

Kirstein SL, Atienza JM, Xi B, Zhu J, Yu N, Wang X, Xu X, Abassi YA.

Assay Drug Dev Technol. 2006 Oct;4(5):545-53.   

Receptor Activity

Label-free and real-time cell-based kinase assay for screening selective and potent receptor tyrosine kinase inhibitors using microelectronic sensor array

Atienza JM, Yu N, Wang X, Xu X, Abassi Y

J Biomol Screen. 2006 Sep;11(6):634-43. Epub 2006 Jul 20.

Angiopoietin-4 Inhibits angiogenesis and Reduces Interstitial Fluid Pressure

Olsen MWB, Ley CD, Junker N, Hansen AJ, Lund EL, Kristjansen PEG.

Neoplasia. 2006 May; 8(5):364-372.

Real-time monitoring of morphological changes in living cells by electronic cell sensor arrays: an approach to study G protein-coupled receptors.

Yu N, Atienza JM, Bernard J, Blanc S, Zhu J, Wang X, Xu X, Abassi YA.

Anal Chem. 2006 Jan 1;78(1):35-43. 

Yeast-derived beta-glucan augments the therapeutic efficacy mediated by anti-vascular endothelial growth factor monoclonal antibody in human carcinoma xenograft models.

Salvador C, Li B, Hansen R, Cramer DE, Kong M, Yan J.

Clin Cancer Res. 2008 Feb 15;14(4):1239-47.

Label-free, real-time monitoring of IgE-mediated mast cell activation on microelectronic cell sensor arrays.

Abassi YA, Jackson JA, Zhu J, O'Connell J, Wang X, Xu X.

J Immunol Methods. 2004 Sep;292(1-2):195-205.

Inactivation of glycogen synthase kinase-3beta contributes to brain-derived neutrophic factor/TrkB-induced resistance to chemotherapy in neuroblastoma cells.

Li Z, Tan F, Thiele CJ.

Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3113-21.